Official draw complete 12 ties
- MjällbyvsMjällby 5.9likelyWinner: Lincoln Red Imps FC / Inter Club d'EscaldesLincoln Red Imps FC 13.5likelyFirst leg: 3–1 vs Inter Club d'Escaldes Leads going into the second legInter Club d'Escaldes 7.5First leg: 1–3 vs Lincoln Red Imps FC Trails going into the second leg
- Winner: KuPS Kuopio / VardarvsKuPS Kuopio 14likelyFirst leg: 2–0 vs Vardar Leads going into the second legVardar 1.6First leg: 0–2 vs KuPS Kuopio Trails going into the second legCrvena ZvezdaCrvena Zvezda 46.5likely
- Winner: Drita / Kauno ŽalgirisvsDrita 13.6likelyFirst leg: 1–1 vs Kauno Žalgiris Level going into the second legKauno Žalgiris 6First leg: 1–1 vs Drita Level going into the second legWinner: Shamrock Rovers / FlorianaShamrock Rovers 19.4likelyFirst leg: 0–2 vs Floriana Trails going into the second legFloriana 4First leg: 2–0 vs Shamrock Rovers Leads going into the second leg









